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Document 3113
DOCN M94A3113
TI HIV disease: clinical spectrum in state of Gujarat, India.
DT 9412
AU Patel AK; Sheth JT; Vasa CV; Patel RK; Saxena DM; B.J. Medical College &
Civil Hospital, Ahmedabad, Gujarat, India.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):150 (abstract no. PB0028). Unique
Identifier : AIDSLINE ICA10/94369462
AB OBJECTIVE: Main objective of this study is to explore the clinical
presentation of HIV disease in State of Gujarat, India. METHODS: The
patients admitted to our institute with high risk behavior and clinical
features related to HIV disease were subjected for HIV testing after
counselling. The study includes only symptomatic individuals with HIV
disease. All patients were investigated for relevant opportunistic and
secondary infections. CD4 & CD8 counts were not done as facility is not
available. RESULTS: Total 31 patients 14 male and 17 female with M:F =
0.824:1. The mode of transmission being sexual route 18 (58.07%)
patients (Heterosexual 17 (54.84%), Homosexual 1 (3.23%), Parenteral
route 13 (41.94%) patients (Blood transfusion 13 (41.94), I.V. drug
abusers Nil, infected needle injury Nil), and vertical transmission Nil.
The common modes of presentation were Fever more than 1 month (80.65%)
weightloss more than 10% of body weight (77.42%). Diarrhoea more than 1
month (41.94%), Oropharyngeal candidiasis (41.94%), Pulmonary and extra
Pulmonary tuberculosis (25.81%), Recurrent Pyogenic infections (12.90%),
generalised lymphadenopathy (12.90%),? Pneumocystis Carinii pneumonia
(12.90%). AIDS Dementia Complex, (9.68%) and Recurrent Herpes Zoster
(9.68%) All the symptomatic patients were admitted to general ward,
treated with general nursing care, proper nutrition and fluid &
electrolyte maintenance. Specific therapy was given for identified
opportunistic infections. Antiretroviral therapy in form of Zidovudine
was given to 3 patients without any clinical improvement. In outcome, 10
patients died and 21 patients were discharged with advise of regular
follow up of which 7 patients were lost to follow up and 14 patients are
regular in follow up. DISCUSSION AND CONCLUSIONS: In India while we are
expecting explosion of AIDS cases in near future, awareness regarding
clinical presentation of patients with HIV disease is important. Apart
from prolonged fever, weightloss and chronic diarrhoea, pulmonary and
extrapulmonary tuberculosis, oropharyngeal candidiasis, recurrent
pyogenic infections and generalised lymphadenopathy are the common modes
of presentation.
DE Acquired Immunodeficiency Syndrome/*PHYSIOPATHOLOGY/THERAPY/
TRANSMISSION AIDS-Related Opportunistic
Infections/PHYSIOPATHOLOGY/THERAPY Female Homosexuality Human HIV
Infections/*PHYSIOPATHOLOGY/THERAPY/TRANSMISSION India Male
Risk-Taking Sex Behavior MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).